02. March 2015 · Comments Off on Clinical Psychopharmacology · Categories: News · Tags: ,

According to Dr. Ana Adan, moderate doses of caffeine consumption can bring benefits in situations of low mood. However, the benefits of caffeine on mood are modest, being limited to mild situations of affectation; Since his administration into more severe clinical circumstances such as major depression, is an insufficient therapeutic strategy for reversing the symptoms of patients. Vigor and fatigue caffeine, consumed both from prepared like coffee, tea or soft drinks Cola or pharmaceutical presentations has accepted the indication of States of drowsiness, asthenia, fatigue or exhaustion, both are these physical type as a psychic. In a study recently published by the prestigious scientific journal Journal of Clinical Psychopharmacology, moderate Caffeine consumption (300-400 mg per day) allows an increase in the force and causing a decrease in fatigue. This work, entitled effects of adenosine 2 antagonists, quercetin and caffeine on the alert and vigor, was developed in California in the base 57 patients, who provided moderate (200 mg) doses of caffeine to check its response in different cognitive aspects, such as intellectual performance, reaction and response to fatigue. The results determined that the administration of caffeine acts on two parameters of surveillance: increases the ability to process stimuli and decreases the time of reaction (response to an unexpected fact).

In parallel, the caffeine appeared increasing vigor and reducing fatigue. The study also reflected that the effects of caffeine in surveillance are detectable only 30 minutes After his administration and remains relatively constant during many hours later. Effect neuroprotective mechanism of action of caffeine is the blockade of adenosine receptors type A1 and A2A., which are widely distributed throughout the brain. The blockade of adenosine receptors produces increases moderated in the transmission of noradrenergic, dopaminergic, serotonergic and cholinergic neurotransmission systems. Action on dopaminergic activity is thought is at the base of the preventive neuroprotector effect of developing Parkinson’s disease, both in males and females provided that these are not subject to estrogenic treatment, adds Dr.

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